The National Institute of Health tracks the number of deaths from opioids. The statistics are discouraging.
It is relatively common to use a combined bar and line graph when there are two vertical axes with differing scales. This example is more puzzling. A stacked bar graph or a line graph with 3 lines would convey the data in a more standard way.
It is not clear that the sex curves are even needed. There appears to be a consistent 60-40 split that could just be mentioned in the text.
The title and subtitle could be rewritten to point out that there has been a 2.8x increase from 2002 to 2015.